Exclusive interview: Sam Altman on Dev Day and AI’s future

Good morning, AI enthusiasts. Sam Altman just painted an image of the long run, and it’s weirder than you think that (but won’t feel that way within the moment).

Between AI agents working autonomously for weeks, billion-dollar firms with zero humans, and a reimagining of what “work” even means, the OpenAI CEO just shared his latest predictions in an exclusive interview with The Rundown at Dev Day 2025.

Catch the total interview with Sam and Rowan on Twitter/X, YouTube, or Spotify.

In today’s AI rundown:

• Sam Altman on Dev Day, AGI, and the long run of labor

• Google releases Gemini 2.5 Computer Use

• Create LinkedIn carousels in ChatGPT with Canva

• Duke’s AI system for smarter drug delivery

• 4 recent AI tools, community workflows, and more

LATEST DEVELOPMENTS

OPENAI

🎙️ Sam Altman on Dev Day, AGI, and the long run of labor

The Rundown: We sat down with OpenAI CEO Sam Altman at Dev Day 2025 for a wide-ranging conversation on the corporate’s recent launches, AGI, the long run of labor, the rise of AI agents, and more.

The main points:

• Altman said AI’s ability for “novel discovery” is beginning to occur, with recent scientists across fields using the tool for breakthroughs.

• Altman thinks the long run of labor “may look less like work” in comparison with now, with a quick transition potentially changing the “social contract” around it.

• He believes Codex is “not distant” from autonomously performing every week of labor, saying the progress of agentic time-based tasks has been disorienting.

• The CEO also highlighted the potential for a zero-person, billion-dollar startup entirely spun up by a prompt being possible in the long run with agentic advances.

Why it matters: Dev Day 2025 gave us a brand new step in each ChatGPT and OpenAI’s agentic tooling evolution, and Altman’s commentary provided a good deeper look into the long run the corporate envisions. But regardless of how strange the AI-driven changes get, Altman stays confident in humanity’s ability to adapt and thrive alongside them.

TOGETHER WITH SYNK

🛡️ Securing the shift to AI native

The Rundown: DevSecCon25 brings together AI and security experts for a free, one-day virtual event exploring how you can empower AI innovation without compromising security — featuring Snyk’s first-ever AI Security Developers Challenge.

Join DevSecCon25 for:

• Keynotes from leaders at Qodo, Ragie AI, Casco, Arcade.dev, WorkOS, and more

• Hands-on demos track covering how you can construct and secure with AI

• An interactive developer challenge where you will solve real AI security problems

Register now.

GOOGLE

🖥️ Google releases Gemini 2.5 Computer Use

The Rundown: Google released Gemini 2.5 Computer Use in preview, a brand new API-accessible model that may control web browsers and complete tasks through direct UI interactions like clicking buttons and filling out forms.

The main points:

• The model works by taking screenshots of internet sites and analyzing them to autonomously execute clicks, typing, and navigation commands.

• Gemini 2.5 Computer Use outperformed rivals, including OpenAI Computer Using Agent and Claude Sonnet 4.5/4 across web and mobile benchmarks.

• It also shows fine quality at the bottom latency of the group, with Google revealing that versions of the model power Project Mariner and AI Mode tools.

Why it matters: While fully agentic computer use remains to be in its early days for mainstream users, the capabilities are rapidly maturing. Beyond the standard examples like booking appointments or shopping, countless time-consuming web tasks and workflows are waiting to be reliably automated.

AI TRAINING

🌟 Create LinkedIn carousels in ChatGPT with Canva

The Rundown: On this tutorial, you’ll learn how you can create skilled LinkedIn carousels in minutes using ChatGPT’s recent Canva app integration, which provides you the flexibility to draft content and design slides all inside a single interface.

Step-by-step:

1. Go to ChatGPT, open a brand new chat, and click on the ‘+’ button to pick Canvas, then prompt: “Write a 5-slide LinkedIn carousel on ‘(your topic)’. Slide 1: A hook. Slides 2-4: One tip each. Slide 5: A CTA. Keep each under 40 words”

2. Refine your content in Canvas, then activate Canva by prompting: “@canva, create a 5-slide LinkedIn carousel using this content [paste slides]. Use a (detailed variety of your selection). Stick with the content copy exactly” (First time: connect Canva in Account Settings → Apps and Connections)

3. Preview the 4 design options ChatGPT generates, select your favorite, and click on the Canva link to open your editable carousel

4. Review each slide in Canva, make any final tweaks, then click Download and choose PDF for LinkedIn documents or PNG for individual slides

Pro tip: Use your brand colours and fonts consistently — when you prompt them in chat, the combination applies them robotically to the carousels.

PRESENTED BY IBM

🌐 Redefining Network Intelligence with AI

The Rundown: IBM Network Intelligence introduces a brand new human-AI model that blends analytical AI with “reasoning” AI — a dual approach developed to assist enterprises filter noise, discover issues, and scale operations seamlessly.

With IBM Network Intelligence, you’ll experience:

• Fast, accurate insights

• AI that scales while humans guide strategy

• Less tool bloat, more efficiency

Learn more.

AI & MEDICINE

💊 Duke’s AI system for smarter drug delivery

The Rundown: Duke University researchers introduced TuNa-AI, a platform that mixes robotics with machine learning to design nanoparticles for drug delivery, showing major improvements in cancer treatment effectiveness.

The main points:

• TuNa tested 1,275 formulations using automated lab robots, achieving a 43% boost in successful nanoparticle creation in comparison with traditional methods.

• The team successfully wrapped a hard-to-deliver leukemia drug in protective particles that dissolved higher and killed more cancer cells in tests.

• In one other win, they cut a potentially toxic ingredient by 75% from a cancer treatment while keeping it just as effective in mice.

• TuNa handles each material selection and mixing ratios concurrently, overcoming limitations of existing methods that may handle just one variable.

Why it matters: Many drugs fail not because they don’t work, but because they will’t reach their targets effectively. AI-powered solutions like TuNa could potentially turn previously shelved drugs into viable options, in addition to help discover and design recent protected and effective therapy options for among the world’s trickiest diseases.

QUICK HITS

🛠️ Trending AI Tools

• 📱 Apps SDK – Chat with and construct apps directly in ChatGPT

• 👁️ Hunyuan-Vision-1.5-Considering – Tecent’s advanced vision-language model

• 🔎 PromptSignal – See how LLMs rank your brand

• 🧫 Petri – Anthropic’s open-source agentic tool for evaluating LLM safety

📰 Every little thing else in AI today

xAI launched v0.9 of its Grok Imagine video model, featuring upgraded quality and motion, native synced audio creation, and recent camera effects.

Tencent released Hunyuan-Vision-1.5-Considering, a brand new multimodal vision-language model that is available in at No.3 on LM Arena’s Vision Arena leaderboard.

Consulting giant Deloitte announced a brand new ‘alliance’ with Anthropic that can deploy Claude across its 470,000 employees.

YouTuber Mr. Beast commented on the rise of AI video capabilities, calling it “scary times” for thousands and thousands of creators making content for a living.

IBM can be partnering with Anthropic to integrate Claude into its AI-first IDE and enterprise software, reporting 45% productivity gains across 6,000 early adopters.

COMMUNITY

🤝 Community AI workflows

Every newsletter, we showcase how a reader is using AI to work smarter, save time, or make life easier.

Today’s workflow comes from reader Nicole B. in Moscow, ID:

“I own a coffee roasting company and used Replit to create a roasting schedule. I gave Replit the coffees and mix recipes, and the quantity of weight green beans lose within the roasting process and we can provide it our coffee orders and get back a complete amount of green coffee that should be roasted for every coffee origin.”

How do you utilize AI? Tell us here.

🎓 Highlights: News, Guides & Events

• Read our last AI newsletter: OpenAI’s biggest Dev Day reveals

• Read our last Tech newsletter: Musk’s Memphis AI empire

• Read our last Robotics newsletter: Optimus now does kung fu

• Today’s AI tool guide: Create carousels in ChatGPT with the Canva app

• RSVP to our next workshop @ 4PM EST Friday: Agent Builder first look

See you soon,

Rowan, Joey, Zach, Shubham, and Jennifer — the humans behind The Rundown